Poster Presentation NSW State Cancer Conference 2023

UNSW Biospecimen Services, incorporating the Health Precincts Biobank: Providing high quality biospecimens and data for translational research   (#199)

Ussha Pillai 1 , Carmel M Quinn 1 , Albert Chetcuti 1 , Lyn M Moir 1 , Carl Power 1 , Anusha Hettiaratchi 1 , Layla Ghourizi 2
  1. UNSW Biospecimen Services, Mark Wainwright Analytical Centre, UNSW Sydney, NSW, 2052
  2. UNSW Cold Storage Services, Pro Vice Chancellor Research Infrastructure, UNSW Sydney, Sydney, NSW, Australia

UNSW Biospecimen Services is a full-service facility supporting all aspects of the use of human biospecimens in research. A complete service is available, ranging from experimental planning, to the collection, processing, storage, and distribution of biospecimens, as well as management of associated data, from both targeted patient populations and healthy subjects. Biospecimen Services can assist researchers requiring bespoke, prospectively collected specimens with all necessary aspects in establishing and managing their own collections.

Under the Biospecimen Services umbrella, the Health Precincts Biobank (formerly the Health Science Alliance, (HSA) Biobank) predominately houses cancer samples, and has a robust governance process to facilitate ethical distribution of biobank specimens; leveraging existing infrastructure within UNSW Biospecimen Services, the biobank collection is expanding to include non-cancer specimens.

The Health Precincts Biobank deals with allocation of already acquired biospecimens. The biobank catalogue housed in OpenSpecimen, a secure web-based biobank database, is searchable online and can be used to initiate communications between the researcher and Biospecimen Services. This is a valuable tool that assists in determining whether the biobank or a tailored collection protocol would best suit researcher needs.

UNSW Biospecimen Services capabilities include:

  • Tailored collection protocols
  • Standardised specimen processing that aligns with biobanking Best Practice
  • Temperature-controlled storage systems that are monitored 24/7, managed through UNSW Cold Storage Services
  • Data linkage from sources including:
    • Clinical data from hospital records e.g., PowerChart; Oncology Information Systems
    • Pathology data from NSW Health Pathology
    • Survival data from the National Death Index, AIHW
    • MBS/PBS data from Services Australia
  • Secure data management through OpenSpecimen, housed on secure UNSW servers

Research can be supported in the following ways:

  • Access to clinical biospecimens from participants with a wide range of diseases
  • Advice and assistance for ethics and governance approvals (for UNSW and SESLHD)
  • Access to the biobank database, OpenSpecimen
  • Long-term managed biospecimen storage facilities
  • Biospecimen preparation, e.g., DNA/RNA from fresh/frozen tissue
  • Formalin Fixed Paraffin Embedded (FFPE) tissue sections; Tumour Microarrays (TMAs)
  • Plasma, DNA/RNA from peripheral blood
  • Provision of cost estimates for inclusion in grant applications

UNSW Biospecimen Services provides a range of services that reduces the burden often placed on researchers requiring access to human biospecimens and/or data for their research.